CANCER COG (2019-2022)

« Recherche translationnelle normande sur l’impact du cancer et des traitements
du cancer sur les fonctions cérébrales »

 
Among the deleterious effects of cancer treatments, neurological toxicities induced by chemotherapy, radiotherapy and new targeted cancer therapies have recently been characterized in the form of more or less long-term cognitive disorders. These cognitive difficulties related to chemotherapy treatments or potentially to new cancer therapies impact the quality of life of patients during treatment but also in the post-cancer period. Depending on the age of the patients, they ask major questions in terms of benefit/risk during treatment, return to work, social relations, and even autonomy. The more specific objective of this program is to assess and understand the impact of new cancer therapies, more specifically immunotherapies and new cerebral radiotherapy modalities, on cognitive functions in cancer patients and to understand their physiopathology through to the analysis of certain plasma biomarkers and with the help of cell cultures and animal models.

 

Partners : ISTCT (Caen), ANTICIPE (Caen), CLCC Baclesse (Caen, FR), DC2N (Rouen, FR), NIMH (Caen, FR), CLCC Becquerel (Rouen, FR)